{"id":33215,"date":"2020-10-19T09:48:41","date_gmt":"2020-10-19T09:48:41","guid":{"rendered":"https:\/\/www.elza-institute.com\/?p=31364"},"modified":"2023-02-01T16:08:31","modified_gmt":"2023-02-01T16:08:31","slug":"bringing-biology-back-to-refractive-surgery","status":"publish","type":"post","link":"https:\/\/www.elza-institute.com\/pt\/bringing-biology-back-to-refractive-surgery\/","title":{"rendered":"Trazer a biologia de volta \u00e0 cirurgia refractiva"},"content":{"rendered":"

At ELZA, we are bringing biology back to refractive surgery, because every silver lining has a cloud.<\/p>\n

At the ELZA Institute<\/a> in Zurich, when we perform very deep excimer laser ablations, it\u2019s usually for one of two reasons.<\/p>\n

The first is therapeutic refractive laser surgery, for example using the excimer laser to treat a deep scar instead of performing lamellar corneal surgery.<\/p>\n

The second is cosmetic: the myopic patient who comes through the door and is at -10 or -11 D. Here, biomechanically, laser-assisted in situ keratomileusis (LASIK) doesn’t make sense (flap creation plus stromal ablation would likely weaken the cornea too much), but photorefractive keratectomy (PRK) might.<\/p>\n

But nothing is straightforward: the problem \u2013 the \u201ccloud\u201d \u2013 with such deep ablations is the wound healing response which results in haze formation. We can stop haze formation by applying a small amount of mitomycin C (MMC) with a sponge immediately after ablation.<\/p>\n

However, the substance is quite toxic (MMC is a chemotherapy drug most often used to treat gastrointestinal, anal, bladder and breast cancers) and it can lead to all sorts of complications. The challenge is to find a way to avoid using it.<\/p>\n

We took a biological approach to what has been classically viewed as a physics problem. If the laser ablation is causing inflammation, can we change how the laser energy is delivered to the cornea in order to cause less inflammation? Long story short: we did, and you can read more about it in Concept Ophthalmologie<\/a>.<\/p>\n

 <\/p>\n

[foogallery id=”33894″]<\/p>\n","protected":false},"excerpt":{"rendered":"

Adopt\u00e1mos uma abordagem biol\u00f3gica ao que tem sido classicamente visto como um problema de f\u00edsica. Se a abla\u00e7\u00e3o por laser est\u00e1 a causar inflama\u00e7\u00e3o, podemos alterar a forma como a energia do laser \u00e9 fornecida \u00e0 c\u00f3rnea de modo a causar menos inflama\u00e7\u00e3o?<\/p>","protected":false},"author":4,"featured_media":33222,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[243,214,95],"tags":[110,125,333,334,599,468,469,332,128,122],"class_list":["post-33215","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-emilio-torres","category-farhad-hafezi","category-scientific-article","tag-complications","tag-cornea","tag-haze","tag-inflammation","tag-laser-complications","tag-schwind","tag-smartsurf","tag-smartsurface","tag-trans-prk","tag-translational-research"],"acf":[],"yoast_head":"\nBringing biology back to refractive surgery - The ELZA Institute<\/title>\n<meta name=\"description\" content=\"At ELZA, we are bringing biology back to refractive surgery to improve how lasers work in refractive surgery and reduce inflammation and haze\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.elza-institute.com\/pt\/bringing-biology-back-to-refractive-surgery\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bringing biology back to refractive surgery - 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