{"id":49253,"date":"2024-09-14T13:56:36","date_gmt":"2024-09-14T13:56:36","guid":{"rendered":"https:\/\/www.elza-institute.com\/?p=44100"},"modified":"2024-09-14T13:56:36","modified_gmt":"2024-09-14T13:56:36","slug":"escrs-today-looks-at-25-years-of-progress-in-cxl","status":"publish","type":"post","link":"https:\/\/www.elza-institute.com\/pt\/escrs-today-looks-at-25-years-of-progress-in-cxl\/","title":{"rendered":"ESCRS Today analisa 25 anos de progressos no CXL"},"content":{"rendered":"
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ESCRS Hoje: Inova\u00e7\u00f5es no Cross-Linking Corneano (CXL): Um olhar sobre 25 anos de progresso<\/strong><\/p>

A Confer\u00eancia ESCRS<\/a>, realizada na semana passada na Fira Barcelona, disponibiliza um jornal \"show daily\", denominado ESCRS Hoje<\/em>.

Este ano, ESCRS Hoje<\/em> O Diretor M\u00e9dico do ELZA, Prof. Farhad Hafezi<\/a>em dois artigos. Porqu\u00ea?<\/p>

O ano de 2024 assinala um marco significativo na oftalmologia: o 25.\u00ba anivers\u00e1rio da entrada do cross-linking corneano (CXL) na pr\u00e1tica cl\u00ednica. Desde a sua cria\u00e7\u00e3o, o CXL transformou o panorama do tratamento do ceratocone e de outras doen\u00e7as ect\u00e1sicas da c\u00f3rnea. Os artigos do ESCRS Today analisaram as origens do CXL e a evolu\u00e7\u00e3o do seu papel na cirurgia refractiva terap\u00eautica.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Da serendipidade \u00e0 norma de cuidados<\/strong><\/p>

Num artigo do Prof. Farhad Hafezi e dos Drs. Mark Hillen e Emilio Torres-Netto, a hist\u00f3ria do CXL remonta ao trabalho inovador dos Professores Theo Seiler e Eberhard Spoerl na d\u00e9cada de 1990. Confrontados com op\u00e7\u00f5es de tratamento limitadas para as ectasias da c\u00f3rnea - em que as lentes de corre\u00e7\u00e3o ofereciam apenas al\u00edvio sintom\u00e1tico e a ceratoplastia era o \u00faltimo recurso - procuraram um m\u00e9todo para travar a progress\u00e3o da doen\u00e7a atrav\u00e9s do refor\u00e7o do estroma da c\u00f3rnea.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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A sua descoberta veio de uma fonte inesperada. Inspirado pela utiliza\u00e7\u00e3o de luz ultravioleta (UV) para endurecer resinas dent\u00e1rias, Seiler imaginou uma abordagem semelhante para a c\u00f3rnea. Combinando a luz UV-A com riboflavina (vitamina B\u2082) como fotossensibilizador, desenvolveram uma t\u00e9cnica para induzir liga\u00e7\u00f5es cruzadas covalentes no colag\u00e9nio do estroma, aumentando efetivamente a rigidez da c\u00f3rnea. Este m\u00e9todo localizou o efeito na c\u00f3rnea, minimizando os danos nos tecidos circundantes.<\/p>

Normaliza\u00e7\u00e3o da terminologia e dos protocolos<\/strong><\/p>

O procedimento, inicialmente conhecido por v\u00e1rios nomes, como \"reticula\u00e7\u00e3o do colag\u00e9nio da c\u00f3rnea\" e \"C3-R\", foi padronizado como \"reticula\u00e7\u00e3o da c\u00f3rnea (CXL)\" durante a Reuni\u00e3o de Peritos em CXL de 2008, em Zurique. O \"protocolo de Dresden\", o m\u00e9todo original de efetuar o CXL, resistiu ao teste do tempo e continua a ser a norma de ouro. Estudos a longo prazo demonstraram a sua efic\u00e1cia em travar a progress\u00e3o do ceratocone durante mais de 15 anos.<\/p>

Olhando para o futuro: O futuro do CXL<\/strong><\/p>

Embora as t\u00e9cnicas tradicionais de CXL continuem a ser eficazes, o futuro reserva-nos avan\u00e7os promissores. Uma dessas inova\u00e7\u00f5es \u00e9 o CXL de dois f\u00f3tons, que utiliza lasers de femtosegundo para reticular seletivamente o tecido da c\u00f3rnea em pontos tridimensionais espec\u00edficos. Esta tecnologia poder\u00e1 expandir as aplica\u00e7\u00f5es do CXL para al\u00e9m das doen\u00e7as ect\u00e1sicas, oferecendo possivelmente novos tratamentos para a miopia e o astigmatismo.<\/p>

Conclus\u00e3o<\/strong><\/p>

Ao celebrarmos 25 anos de CXL, \u00e9 evidente que o campo continua a evoluir. Inova\u00e7\u00f5es como o CXL de dois f\u00f3tons e as cirurgias refractivas terap\u00eauticas personalizadas est\u00e3o a expandir os horizontes do que \u00e9 poss\u00edvel no tratamento da c\u00f3rnea.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Melhorar a qualidade de vida atrav\u00e9s da cirurgia refractiva terap\u00eautica<\/strong><\/p>

Farhad Hafezi discutiu o impacto da cirurgia refractiva terap\u00eautica na qualidade de vida dos doentes durante a Cimeira Refractiva Global no Congresso da ESCRS de 2024 em Barcelona. Ele enfatizou a distin\u00e7\u00e3o entre acuidade visual e qualidade visual, defendendo tratamentos que abordam as aberra\u00e7\u00f5es da c\u00f3rnea para melhorar a fun\u00e7\u00e3o visual geral.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Estudos de casos que destacam t\u00e9cnicas avan\u00e7adas<\/strong><\/p>

O Prof. Hafezi apresentou v\u00e1rios casos em que foram utilizadas t\u00e9cnicas avan\u00e7adas de diagn\u00f3stico e de cirurgia:<\/p>

  • Cicatriz ap\u00f3s ceratite:<\/strong>\u00a0Ao libertar a tra\u00e7\u00e3o causada pelas cicatrizes e ao realizar uma abla\u00e7\u00e3o superficial guiada por uma frente de onda, foram obtidas melhorias significativas na qualidade visual ao longo de 6 a 12 meses.<\/p><\/li>

  • Doentes com ceratocone:<\/strong>\u00a0A combina\u00e7\u00e3o de uma remo\u00e7\u00e3o limitada de tecido atrav\u00e9s de uma abla\u00e7\u00e3o superficial guiada pela frente de onda com CXL imediato fortaleceu a c\u00f3rnea sem comprometer a integridade estrutural, melhorando a acuidade visual \u00e0 dist\u00e2ncia corrigida (CDVA).<\/p><\/li>

  • Complica\u00e7\u00f5es p\u00f3s-PRK:<\/strong>\u00a0Em doentes com coma horizontal elevado devido a procedimentos PRK desactualizados, a recentragem e o alargamento da zona \u00f3tica conduziram a melhorias not\u00e1veis na qualidade visual.<\/p><\/li><\/ul>

    Uma abordagem hol\u00edstica \u00e0 corre\u00e7\u00e3o da vis\u00e3o<\/strong><\/p>

    O Prof. Hafezi sublinhou a import\u00e2ncia de abordar tanto a estrutura da c\u00f3rnea como a fun\u00e7\u00e3o visual. Ao tirar partido dos avan\u00e7os no diagn\u00f3stico por imagem e no planeamento de tratamentos personalizados, os oftalmologistas podem oferecer solu\u00e7\u00f5es que melhoram significativamente a qualidade de vida dos doentes.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

    Inova\u00e7\u00f5es no Cross-Linking Corneano (CXL): Um olhar sobre 25 anos de progresso<\/p>","protected":false},"author":4,"featured_media":49171,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[243,214,1,96],"tags":[209,105,116,130,100,133,134,278,1000,532,104,122],"class_list":["post-49253","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-emilio-torres","category-farhad-hafezi","category-general-news","category-popular-press","tag-basic-research","tag-corneal-infection","tag-corneal-ulcer","tag-cross-linking","tag-cxl","tag-epi-off","tag-epi-on","tag-escrs","tag-escrs-today","tag-oxygen","tag-pack-cxl","tag-translational-research"],"acf":[],"yoast_head":"\nESCRS Today looks at 25 Years of Progress in CXL - The ELZA Institute<\/title>\n<meta name=\"description\" content=\"This year, ESCRS Today featured ELZA\u2019s Medical Director, Prof. Farhad Hafezi, in two articles. 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Porqu\u00ea? Bem, por duas boas raz\u00f5es...","breadcrumb":{"@id":"https:\/\/www.elza-institute.com\/escrs-today-looks-at-25-years-of-progress-in-cxl\/#breadcrumb"},"inLanguage":"pt-PT","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.elza-institute.com\/escrs-today-looks-at-25-years-of-progress-in-cxl\/"]}]},{"@type":"ImageObject","inLanguage":"pt-PT","@id":"https:\/\/www.elza-institute.com\/escrs-today-looks-at-25-years-of-progress-in-cxl\/#primaryimage","url":"https:\/\/www.elza-institute.com\/wp-content\/uploads\/2024\/09\/featured-image.jpg","contentUrl":"https:\/\/www.elza-institute.com\/wp-content\/uploads\/2024\/09\/featured-image.jpg","width":1200,"height":600},{"@type":"BreadcrumbList","@id":"https:\/\/www.elza-institute.com\/escrs-today-looks-at-25-years-of-progress-in-cxl\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.elza-institute.com\/"},{"@type":"ListItem","position":2,"name":"News","item":"https:\/\/www.elza-institute.com\/general-news\/"},{"@type":"ListItem","position":3,"name":"ESCRS Today looks at 25 Years of Progress in CXL"}]},{"@type":"WebSite","@id":"https:\/\/www.elza-institute.com\/#website","url":"https:\/\/www.elza-institute.com\/","name":"O Instituto ELZA","description":"Swiss EyeCare no seu melhor","publisher":{"@id":"https:\/\/www.elza-institute.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.elza-institute.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-PT"},{"@type":"Organization","@id":"https:\/\/www.elza-institute.com\/#organization","name":"O Instituto ELZA","url":"https:\/\/www.elza-institute.com\/","logo":{"@type":"ImageObject","inLanguage":"pt-PT","@id":"https:\/\/www.elza-institute.com\/#\/schema\/logo\/image\/","url":"https:\/\/www.elza-institute.com\/wp-content\/uploads\/2016\/04\/ELZA-logo-V4.jpg","contentUrl":"https:\/\/www.elza-institute.com\/wp-content\/uploads\/2016\/04\/ELZA-logo-V4.jpg","width":1181,"height":453,"caption":"The ELZA Institute"},"image":{"@id":"https:\/\/www.elza-institute.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/ELZA.Institute\/","https:\/\/x.com\/ELZA_Institute","https:\/\/www.linkedin.com\/company\/elza-institute?trk=top_nav_home"]},{"@type":"Person","@id":"https:\/\/www.elza-institute.com\/#\/schema\/person\/e3929262886a5a60dd6965a6bc721d15","name":"Mark Hillen","url":"https:\/\/www.elza-institute.com\/pt\/author\/markhillen\/"}]}},"_links":{"self":[{"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/posts\/49253","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/comments?post=49253"}],"version-history":[{"count":0,"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/posts\/49253\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/media\/49171"}],"wp:attachment":[{"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/media?parent=49253"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/categories?post=49253"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.elza-institute.com\/pt\/wp-json\/wp\/v2\/tags?post=49253"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}