Thyroid gland function and the cornea

Underactive thyroid

An underactive thyroid (also known as hypothyroidism), can have a number of causes: it may be congenital, spontaneous, or an expression of various diseases (such as autoimmune thyroiditis) or can arise as a result of surgery to, or irradiation of, the thyroid gland.

Hypothyroidism has a direct effect on the biomechanics of the cornea. The exact mechanism of action is not yet known. Under certain circumstances, hypothyroidism may affect keratoconus and may be a contra-indication for (reason not perform) perform laser refractive surgery.

In addition, many women have an underactive thyroid during pregnancy.

The relationship

A connection between hypothyroidism and keratoconus has been suspected for decades:

  • In 1936, Appelbaum reported that patients with keratoconus have unusual signs of hypothyroidism.
  • In 1953, King showed that keratoconus is common after removal of the thyroid gland.
  • In 1999, Kocak described that autoimmune diseases of the thyroid lead to bilateral keratoconus.

Hypothyroidism and corneal topography

A scientific article of Prof. Hafezi’s, published in 2014 in the Journal of Refractive Surgery clearly showed the association between hyperthyroidism and changes in corneal topography. Such changes are then accompanied by considerable fluctuations in vision.

Hypothyroidism and keratoconus

In this 53-year-old woman, keratoconus developed following a radioactive iodine therapy for Graves’ disease. No signs of keratoconus were present in the cornea prior to Graves’ disease.

2012 - 2013

OD

OS

Hormones and the cornea

The ELZA Institute

EN | DE

Augeninstitut ELZA
4.7
Based on 80 reviews
powered by Google
Thomas S.
Thomas S.
09:37 07 Jul 21
My left eye had to be operated on because of a cataract. As I had an Artiflex lens implanted a few years ago, it had to... be removed first before a modern lens could be implanted to correct the cataract. Prof. Hafezi treated me in an very competent and friendly manner. I am very happy with the result.read more
Selma A. Rahim
Selma A. Rahim
19:45 02 Jul 21
Dr. Hafezi.. the KING OF CXL🤴
Gianluca Ricci
Gianluca Ricci
12:46 10 Apr 21
Great team and service!
rehaneyecare
rehaneyecare
05:36 08 Apr 21
Excellent surgeon
Steven H.A
Steven H.A
16:13 11 Jan 21
Prof. F. Hafezi s expertise is enormous and he has a very pleasant and calm nature which gives the patient... security.Thank youread more
Online Commande
Online Commande
09:19 05 Dec 20
Totally creepy, very arrogant Prof.He just want your money.It may explain, why this Prof. is not in the center of the... city of Zürich and why he has been thrown away from University of Geneva.read more
Elena Churilova
Elena Churilova
10:06 17 Nov 20
At the moment, 3 months have passed since the moment I made laser vision correction in this clinic. and I can say that... I am happy that I chose this particular clinic and Prof. F. Hafezi. The entire staff of the clinic is very friendly, treats patients with sympathy and patience if they are nervous before surgery (my big gratitude to Aida Alili for all support and patience). The doctor Hafezi and other doctors of the clinic are very professional and ready to explain to you as many times as you need. I can only recommend!read more
Next Reviews
Augeninstitut ELZA
4.7
Based on 80 reviews
powered by Google