Salzmann nodular degeneration is a slowly progressive condition in which collagen-rich nodules form on the surface of the cornea. These deposits often develop in response to long-standing irritation, such as chronic inflammation or decades of contact lens wear. The nodules can impair vision by reducing corneal transparency and distorting its shape.
On examination, Salzmann nodules appear as elevated areas on the cornea and can be clearly visualized with optical coherence tomography (OCT). In the figure shown, the whitish elevation in the lower portion of the scan corresponds to one of these nodules. The condition progresses slowly, often over many years, and may initially go unnoticed until visual symptoms arise.
The nodules reduce corneal transparency (see top left image), making the eye’s “window to the world” appear cloudy. In addition, they can distort the overall corneal shape, as shown by the green-blue areas in the corneal topography (top right image). This distortion results in irregular astigmatism and blurred vision.
Salzmann nodules can be surgically removed under a microscope. However, recurrence is possible, typically after 8 to 10 years. Repeat removal (even second or third procedures) is feasible if necessary.
Around six months after surgery, we assess whether the cornea’s shape has normalized. Why six months? Because the cornea responds slowly to change. If irregular curvature persists, we may further refine the corneal surface using an excimer laser (wavefront-guided transPRK) to improve vision.
PREVIOUSGet in touch
During office hours.
Email us.
Make an appointment, and come to see us.
Thank you for writing a review on google.
Contact us here, we will get in touch with you.
Zoom online consultation for our international patients.
Contact us here, we will get in touch with you.
Contact us here, we will get in touch with you.
