The human cornea must be mechanically stable as a structure. One speaks of the biomechanics of the cornea. In recent years there is increasing evidence that hormones, especially during pregnancy, can negatively affect corneal biomechanics. Our group is one of the international pioneers of this branch of research.
During pregnancy, many alterations take place in the human body. It has been known for decades that a so-called “myopic shift” takes place in late pregnancy, so the human eye becomes more short-sighted. The causes of this are not yet fully understood, but it is believed that the cornea in late pregnancy stores water and thereby changes their refractive index. These hermetic changes usually return in the first months after pregnancy
It has been known for a number of years now that oestrogen can directly affect the cornea. Increased oestrogen levels during pregnancy can have a direct impact on the biomechanical stability of the cornea. In other words, the cornea becomes “softer” at the end of the pregnancy. This can have a number of consequences.
Bad vision and pregnancy
There is increasing evidence that the under-production of thyroid stimulating hormone, TSH, has a direct impact on the biomechanics of the cornea and therefore, good vision. Our research group has been a trailblazer here; read more about our work here.