ELZA’s Medical Director, Prof. Farhad Hafezi, MD, PhD, FARVO, was featured in a recent video interview by Healio/Ocular Surgery News during the 2024 ESCRS meeting in Barcelona. In this interview, he provided insights into the novel application of cross-linking in the femto-CAIRS (Corneal Inlay for Astigmatism Reduction Surgery) procedure, particularly for treating keratoconus.
Prof. Hafezi detailed how the integration of cross-linking enhances the mechanical properties of the ring segments used in the femto-CAIRS technique. By applying cross-linking outside the body, the ring segments become stiffer and more compact, which facilitates easier insertion into the corneal tunnel. Additionally, this process ensures the sterility of the segments by eliminating keratocytes.
During the procedure, Prof. Hafezi highlighted the ability to use significantly higher energy levels—up to 60 J/cm2—compared to the traditional Dresden protocol. This increased energy enhances the stiffness of the corneal segments, improving their integration within the host tissue. He noted that, within a week, the segments integrate effectively, although they initially exhibit higher stiffness.
Prof. Hafezi also discussed the ongoing development of nomograms to optimize this approach, focusing on the interplay between tissue volume and intrinsic stiffness in achieving successful outcomes. He emphasized that this method represents a departure from conventional techniques, with its high fluence cross-linking approach, termed ADA-cross-linking, denoting a significant advancement in corneal surgery.
The femto-CAIRS procedure and the cross-linking technique have the potential to redefine treatment options for keratoconus patients, illustrating the ELZA Institute’s commitment to advancing corneal health and surgical practices.
For more details, view the full interview here.
