In May 2025, Nikki Hafezi, MAS IP ETHZ, ELZA’s CEO, and her local team in Uzbekistan, initiated the P21 screening program in the Bukhara region of that country. Over four days, approximately 400 children from the region – including 250 from a local boarding school – underwent comprehensive health assessments. This initiative exemplifies a multidisciplinary approach to the early detection of conditions impacting childhood vision and overall health.
Focus on Keratoconus Screening
Keratoconus remains a leading cause of preventable blindness worldwide. The P21 program prioritised early identification of this corneal ectasia through advanced ophthalmic screening. A penta camera system was deployed to evaluate corneal shape and thickness, facilitating timely diagnosis and intervention. Early detection is essential to halt disease progression and preserve vision.
Multidisciplinary Health Assessments
Beyond ophthalmology, the program integrated screenings in dentistry, ENT (ear, nose, and throat), and neurology. Dental examinations focused on identifying caries, which can disproportionately affect children with systemic conditions. ENT evaluations screened for hearing loss, while neurological assessments targeted sensory functions critical for developmental monitoring. This holistic strategy reflects current understanding that multisystem surveillance enhances overall health outcomes in paediatric populations.
Community Engagement and Infrastructure
The ELZA team collaborated closely with local authorities, including the Agency of Social Protection and the boarding school administration. Utilizing half of the social protection building allowed for efficient patient flow across departments. A dedicated waiting area provided children a safe, engaging environment with toys and supervised activities, supporting a child-friendly experience during potentially stressful examinations.
Leadership and Global Collaboration
Nikki Hafezi is also a co-founder of the Light for Sight Foundation, and spearheaded this outreach. Her role encompasses clinical innovation and international cooperation, aiming to reduce preventable blindness through education and screening. The P21 program, operated in partnership with Light for Sight exemplifies how global expertise can deliver sustainable local impact.
Implications and Future Directions
Programs like P21 underline the necessity of integrating ophthalmic care with broader paediatric health services. The model implemented in Bukhara can inform similar initiatives in regions with limited access to specialised screening. Continued monitoring of outcomes will guide refinement and expansion of such multidisciplinary approaches.
